Our current medical care system is
based on the treatment of disease. We have the knowledge, technology,
and expertise to prevent or delay the onset of many of the symptoms
associated with aging, and in some cases to reverse them. It is
my opinion that it is important to look in areas that are often
not considered by my mainstream colleagues. By doing this, I believe
we can guarantee a higher quality of life as we age.
Continued specialization by physicians dealing with specific symptom
complexes limited to one or two organ systems plus our country’s
insurance reimbursement system based on disease codes, do not allow
even the most caring physicians to work within the existing framework
to help patients in their quest for optimal health. As we learn
more and more about the aging process, it has become painfully obvious
that traditional medicine is not equipped to realistically help
the patient population interested in staying healthy.
A new specialty area has arisen called “Age Management Medicine”
– managing the aging process with hormonal and metabolic therapies
to keep our bodies healthy – the ultimate preventive medicine.
Contrary to some who would sensationalize, aging is not a disease,
but rather a process, that hopefully, we will all experience over
a lengthening period of time. The diagnostic and therapeutic tools
we now have to manage aging, and those that will become available
in the near future, have produced a clarion call for this new specialty.
Opportunities are becoming available to not only maintain, but to
regain youthful vigor and to live healthier, higher quality lives.
Will we live longer? Probably, but we have not proven that yet.
In Age Management Medicine we believe that we can improve the quality
of life by delaying chronic disease through the use of five principles:
1) education, 2) low glycemic diet, 3) exercise, 4) pharmaceuticals
when indicated, and 5) hormone modulation. The assumption that aging
is normal, with the decline in hormones and other bodily functions,
is wrong. Many of the aging symptoms are really a disease and should
be treated. Based on valid lab findings, replacement of hormones
to the mean level of a 30-year-old should be the goal.
Hormone needs will vary widely by individual patient. In the case
of female hormone replacement therapy in mainstream medicine, the
hormones used have been equine hormones which do not work the same
in humans. Natural “bio-identical” hormones are available
and are much more effective without the negative side effects. Menopause
involves much more than the loss of estrogen and progesterone. Menopause
is part of something much bigger involving aging of your entire
being. During menopause almost all the hormones in your body become
deficient and the entire endocrine system must be evaluated in order
to design hormonal and metabolic therapies to help manage the aging
process and restore hormonal balance, with the aim of regaining
and preserving youthful vigor.
Andropause is part of the aging process sometimes called “male
menopause.” Andropause involves much more than the loss of
testosterone; almost all the hormone levels in your body are becoming
deficient or partially deficient after the age of 35. Hormonal and
metabolic therapies can: 1) increase energy level – including
sexual energy, 2) reduce body fat, 3) increase lean muscle, 4) increase
bone density, 5) improve cognitive function, and 6) strengthen your
immune system. Perhaps more importantly, testosterone therapy has
been shown to reduce heart disease.
In addition to gender specific hormones, any individual may have
many other hormones that should be supplemented to reach the optimal
level, including Human Growth Hormone and DHEA, among others. There
is evidence that growth hormone deficiency in adults is deleterious,
increasing the risk of death from cardiovascular disease. As compared
with age-matched and sex-matched normal subjects, adults with growth
hormone deficiency have increased fat mass, reduced muscle mass
and strength, smaller hearts and lower cardiac output, lower bone
density, and higher serum lipid concentrations. They also have decreased
vitality, energy, and physical mobility, emotional liability, feelings
of social isolation, and disturbances in sexual function, despite
adequate correction of hormonal deficiencies other than growth hormone
deficiency.
In 1990 it was recognized that there are benefits of using growth
hormone in the treatment of normal aging. In fact, there is absolutely
no difference between the clinical signs and symptoms of aging and
those of adult growth hormone deficiency described in the previous
paragraph. The late Dr. Daniel Rudman first described the benefits
of growth hormone therapy in normal aging adults. Dr. Rudman published
a landmark article in the New England Journal of Medicine
on July 7, 1990. In his article, Dr. Rudman showed that by putting
healthy aging men on growth hormone for six months, he was able
to decrease their body fat by 14.4%, increase muscle mass by 8.8%,
increase skin thickness by 7.1%, and increase lumbar bone density
by 1.6%. These exciting findings clearly inaugurated the movement
to supplement growth hormone in healthy aging adults, which today
is becoming commonplace.
The goals of growth hormone therapy in adults are to restore normal
body composition, improve muscle and cardiac function, normalize
serum lipid concentrations, and improve the quality of life. Healthful
living depends on balancing our hormones at the upper end of the
normal range and regaining and maintaining optimal health and vigor.
Hugo Pribor, M.D., Ph.D., FCAP
is the medical director of Pribor and Associates, LLC and practices
anti-aging medicine in Tampa, FL and Nashville, TN. (813) 282-7173
www.hpribor.com
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